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Low vaccination rates for influenza viruses and the lack of an HSV vaccine underscore the need for a new approach to reduce viral transmission. Researchers have now used a clinical-grade antiviral chewing gum to substantially reduce viral loads of two herpes simplex viruses and two influenza A strains in experimental models.
Researchers reveal why young plants may be more vulnerable to disease (link is external)
A new study reveals an evolutionary trade-off that young plants face to develop disease resistance.
Best methods for growing Atlantic sea scallops (link is external)
A new study compares two scallop farming methods, ear-hanging and lantern net culture, over a complete grow-out cycle to determine which approach yields the best results for commercial growers. The study found that scallops grown with ear-hanging culture had slightly larger shell heights, about 1-4% greater than those in lantern nets. More significantly, ear-hanging scallops had up to 12% more adductor muscle weight. Researchers also found that ear-hanging scallops grew more quickly in optimal conditions, which are between 50 and 59 degrees Fahrenheit, but were more affected by colder winter temperatures than those in lantern nets.
Oxygen is running low in inland waters, and humans are to blame (link is external)
Rivers, streams, lakes, and reservoirs aren't just scenic parts of our landscape -- they're also vital engines for life on Earth. These inland waters 'breathe' oxygen, just like we do. But a new study shows that we've been suffocating them during the last century, an era also known as the Anthropocene. The research reveals that the way oxygen is produced and used in inland waters has dramatically changed since 1900. The culprit? Human activities.
Planetary health diet and Mediterranean diet associated with similar survival and sustainability benefits (link is external)
A cohort study was conducted in Spain to compare the health and environmental benefits of the Planetary Health Diet (PHD) and the Mediterranean Diet. Compared to participants with low adherence, higher adherence to both diets was similarly associated with lower all-cause mortality and with comparable low environmental impact. This study highlights the advantages of the plant-based diets, with wider adoption of healthy and sustainable diets needed to prevent excess premature deaths worldwide.
How cells repair their power plants (link is external)
Damage to the mitochondria, the 'power plants' of the cells, contributes to many diseases. Researchers now describe how cells with defective mitochondria activate a special recycling system to eliminate damaged genetic material.
Novel genomic screening tool enables precision reverse-engineering of genetic programming in cells (link is external)
Collaborative research defines a novel approach to understanding how certain proteins called transcription factors determine which genetic programs will drive cell growth and maturation. The method, called 'Perturb-multiome,' uses CRISPR to knock out the function of individual transcription factors across many blood cells at once. The researchers then perform single-cell analyses on each cell to measure the effects of the editing, including identifying which genes have been turned on or off and which genes are accessible (based on epigenetic markers).
Century-old clues reveal hidden threat to Australian songbird (link is external)
A hidden threat facing one of Australia's most iconic birds has been uncovered in a new study. The critically endangered regent honeyeater once numbered in the hundreds of thousands, but their population has dwindled to fewer than 300. By analysing the DNA of museum specimens more than 100 years old and comparing it to modern samples, the team discovered that despite a population decline of 99 per cent, this has not been entirely mirrored by genetics. The bird has lost 9 per cent of its genetic diversity.
A Leap in viral research: More sensitive viral RNA detection (link is external)
Researchers have unveiled innovative, label-free ratiometric fluorosensor designed for the selective and sensitive detection of enteroviral RNA. The research promises to deliver even more advanced and effective detection methods, reinforcing the importance of interdisciplinary collaboration in addressing global health challenges.
Suspected fibrocartilaginous embolus in Asian small-clawed otter (Aonyx cinereus) (link is external)
A research team investigated the case of a male Asian small-clawed otter that fell down the stairs while sleeping, after which it developed left-sided paralysis.
Soil conditions significantly increase rainfall in world's megastorm hotspots (link is external)
Storm forecasting is traditionally based on studying atmospheric conditions but ground-breaking research that also looks at land surface conditions is set to transform early warning systems in tropical regions. This will enable communities to better adapt to the destructive impacts of climate change. The new study has shown that a large contrast in soil moisture levels over a range of hundreds of kilometers results in atmospheric changes that increase rainfall area and amount in several megastorm hotspots globally. This increase ranges from 10 to 30% depending on the region and size of the storm.
Discovery of bacteria's defense against viruses becomes a piece of the puzzle against resistance (link is external)
Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades. In a new study, researchers show that the emergence of resistance can be understood in the mechanism of how bacteria build up defenses against being infected by viruses. It is about genes in the bacterium that interfere with the attacking virus's ability to multiply.
How can science benefit from AI? Risks? (link is external)
Researchers from chemistry, biology, and medicine are increasingly turning to AI models to develop new hypotheses. However, it is often unclear on which basis the algorithms come to their conclusions and to what extent they can be generalized. A publicationnow warns of misunderstandings in handling artificial intelligence. At the same time, it highlights the conditions under which researchers can most likely have confidence in the models.
How a small number of mutations can fuel outbreaks of western equine encephalitis virus (link is external)
New research shows how small shifts in the molecular makeup of a virus can profoundly alter its fate. These shifts could turn a deadly pathogen into a harmless bug or supercharge a relatively benign virus, influencing its ability to infect humans and cause dangerous outbreaks.
Exposure to wildfire smoke linked with worsening mental health conditions (link is external)
Exposure to fine particulate air pollution (PM2.5) from wildfire smoke was associated with increased visits to emergency departments (ED) for mental health conditions, according to a new study.
Research uncovers hidden spread of one of the most common hospital-associated infections (link is external)
C. difficile (C. diff) is one of the most common and contagious hospital-acquired infections. Research has found that C. diff spreads more than three times more than previously thought. C. diff can spread covertly from surface to surface and remain undetected for weeks until it infects a patient. The results could spur more rigorous preventive measures that stop hidden spread of the disease.
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