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Engineering smart delivery for gene editors (link is external)

Environmental Feed -

A research team has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before. Their technology, ENVLPE, uses engineered non-infectious virus-like particles to precisely correct defective genes -- demonstrated successfully in living mouse models that are blind due to a mutation. This system also holds promise for advancing cancer therapy by enabling precise genetic manipulation of engineered immune cells making them more universally compatible and thus more accessible for a larger group of cancer patients.

Six ape genomes sequenced telomere-to-telomere (link is external)

Environmental Feed -

Comprehensive reference genomes have now been assembled for six ape species: siamang (a Southeast Asian gibbon), Sumatran orangutan, Bornean orangutan, gorilla, bonobo and chimpanzee. Areas of their genomes previously inaccessible because of structural complexity have now mostly been resolved. The resource is already lending itself to comparative studies that offer new insights into human and ape evolution, and into what underlies the functional differences among these species.

What's on the menu for Ryukyu's minute mammals? (link is external)

Environmental Feed -

Japan's Ryukyu Islands, which includes Okinawa, are the exclusive home to two rare mammals, the Amami rabbit and Ryukyu long-furred rat. These animals are hard to observe, but conservationists wish to find out specific details about their diets. So researchers inspected the teeth from deceased specimens to find out what the animals were eating, and at different times. Their findings show the rabbits have consistent diets, whereas the rats' change with the seasons.

Nasal spray H5N1 avian influenza vaccine developed (link is external)

Environmental Feed -

Scientists have pioneered an influenza virus vector-based nasal spray vaccine platform and developed a nasal spray H5N1 avian influenza vaccine. During the early COVID-19 pandemic, this platform enabled the rapid development of a nasal spray vaccine in collaboration with mainland China's Wantai BioPharm. After completing Phase 1-3 clinical trials, it was approved in 2022 as the world's first nasal spray COVID-19 vaccine.

In Guatemala, painted altar found at Tikal adds new context to mysterious Maya history (link is external)

Environmental Feed -

Just steps from the center of Tikal, a 2,400-year-old Maya city in the heart of modern-day Guatemala, a global team of researchers has unearthed a buried altar that could unlock the secrets of a mysterious time of upheaval in the ancient world. The altar, built around the late 300s A.D., is decorated with four painted panels of red, black and yellow depicting a person wearing a feathered headdress and flanked by shields or regalia. The face has almond-shaped eyes, a nose bar and a double earspool. It closely resembles other depictions of a deity dubbed the 'Storm God' in central Mexico.

Long-term health impacts of flooding revealed (link is external)

Environmental Feed -

A comprehensive study of the long-term health impacts of flooding -- via analysis of over 300 million hospitalizations records in eight countries prone to flooding events -- has found an increased risk of 26 per cent of all diseases serious enough to require hospitalization. This impact on the health of communities lasts up to seven months post event.

Role of social workers in addressing marginalized communities bearing brunt of climate disasters (link is external)

Environmental Feed -

A researcher spent a year living in a jjokbang-chon, an extremely impoverished neighborhood in Seoul, South Korea. While there, he calculated residents' carbon footprints, finding they contribute much less to climate change than their fellow citizens, and detailed how they suffer the effects of extreme heat and other climate issues. He advocates for social work to take a role in addressing such climate injustice in a way that does not remove already limited resources from such populations.

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